If there are two or more relatives with ovarian cancer in your family, or one relative with ovarian cancer and one with breast cancer before the age of 50 years (or two relatives with breast cancer before the age of 60 years), then you may be at high risk of developing ovarian cancer. In certain cases, this risk could be as high as one in two by the age of 70 years. -- See Dr Adam Rosenthal, Patients at High Risk of Ovarian Cancer.