Tumour Devascularisation by Nanoknife

Hammersmith Hospital's Professor Edward Leen describes in a case study how Nanoknife can be used to treat highly complex forms of metastasised tumour. He reviews the case of Mrs MR who had been previously operated on but who had worsening and highly involved liver cancer. He says, "This was a very serious and complex case".

The full medical description of her condition was that she had “recurrent progressive liver metastases, a year after having had a previous right hepatectomy for rupture of the adrenocortical liver metastases and an attempt to repeat a resection of the new liver metastases failed”.

In the case study, Prof Leen explains the decision making process, why it was felt that Nanoknife was an appropriate option and the outcome of the operation.

He says that a subsequent CT scan performed six weeks later showed, "significant involution of the ablated zone with approximately 50% reduction in size". He goes onto say, "Perhaps more importantly, all blood vessels that had been supplying the tumour had been destroyed (this is known as devascularisation, which is a critical step in ensuring that the tumour cannot grow back again). Fifteen months later and at follow-up there had been no recurrence, or return of the tumour."

For further information - see New Cancer Treatment Nanoknife

A fluid that transports oxygen and other substances through the body, made up of blood cells suspended in a liquid. Full medical glossary
Abnormal, uncontrolled cell division resulting in a malignant tumour that may invade surrounding tissues or spread to distant parts of the body. Full medical glossary
The abbreviation for computed tomography, a scan that generates a series of cross-sectional x-ray images Full medical glossary
A large abdominal organ that has many important roles including the production of bile and clotting factors, detoxification, and the metabolism of proteins, carbohydrates and fats. Full medical glossary
Secondary tumours’ that result from the spread of a malignant tumour to other parts of the body. Full medical glossary
The spread of a malignant tumour to other parts of the body. Full medical glossary
Continuously increasing in extent or severity. Full medical glossary
The surgical removal of part of the body. Full medical glossary
An abnormal swelling. Full medical glossary
Relating to blood vessels. Full medical glossary
The process of blood flowing through the area. Full medical glossary